The age of patients undergoing a stem cell transplant or CAR T-cell therapy is increasing, but older patients are often not as fit as younger adults. Transplant and CAR T-cell therapies can be modified to increase the likelihood of success for old adults.

Graft-versus-host disease (GVHD) is a condition that can occur after a stem cell using donor cells (an allogenic transplant). This presentation describes how GVHD can affect the mouth, esophagus, stomach, small intestine, large intestine and liver.

Problems with sleeping can exacerbate the fatigue and depression that often accompanies a stem cell transplant. This presentation reviews many sleep issues like insomnia that can complicate recovery after transplant, and describes effective remedies for these problems.

Bone marrow transplant survivors have an increased risk of developing a second or “secondary” cancer later in life. This video discusses risk factors for developing a secondary cancer, cancers most frequently seen after transplant and monitoring and testing that should be done periodically to catch second cancers early when they are easiest to treat. (Throughout the talk, bone marrow transplant refers both to bone marrow transplants and stem cell transplants, as well as cord blood transplants.)

Autologous stem cell transplants are a treatment option primarily for patients with multiple myeloma and non-Hodgkin lymphoma. High-dose chemotherapy is part of the treatment and can destroy cancer cells as well as healthy blood cells. Although side effects do occur after an autologous stem cell transplant, most patients can expect a return to normal, healthy life after transplant.

Long-term health consequences of stem cell transplant using donor cells (an allogeneic transplant) are very real, although they affect a minority of patients and can often be treated effectively. This presentation reviews the most common problems following an allogeneic transplant and the therapies available to treat them.

Stem cell transplantation typically involves chemotherapy and radiation. These treatments, as well as other medications transplant recipients receive, and complications after transplant such as graft-versus-host disease (GVHD), can negatively affect a woman’s sexual health. This presentation discusses a variety of sexual health difficulties that can occur after transplant, and how to manage them.