Managing Ocular Graft-versus-Host Disease
Managing Ocular Graft-versus-Host Disease
Presenter: Rahul Tonk MD, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine
Summary:
Chronic ocular graft-versus-host disease (GVHD) affects more than 50% of patients who have chronic GVHD. A variety of therapies are available and should be approached in a step-ladder manner.
Highlights:
• Chronic GVHD can affect the eye surface, eyelid and inner eye
• Chronic GVHD can cause dry eyes, ulcerations, scarring and cataracts that affect vision
• Most patients with ocular GVHD have a mild case of the disease
• Management should follow a step-ladder approach
- Control your environment
- Lubricants
- Try tear preservation
- Eye surface support
- Immunosuppression
- Surgery
- • If you have, or are at risk of developing, ocular GVHD, you should be seen by an ophthalmologist who is a cornea specialist.
Thank you to Jazz Pharmaceuticals for supporting this presentation.